Hydrochloric Acid → HCID 67409879, compound

HRID 1401274Notes

Reaction equation

HRID 1401274 reaction equation
[Cl:1][C:2]1[C:7]([I:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]1[O:10][C:11]2[C:16]([C:17](=[O:19])[CH:18]=1)=[C:15]([OH:20])[CH:14]=[C:13]([OH:21])[C:12]=2[C@@H:22]1[CH2:26][CH2:25][N:24]([CH3:27])[C@H:23]1[CH2:28][OH:29].Cl>CO>[ClH:1].[Cl:1][C:2]1[C:7]([I:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]1[O:10][C:11]2[C:16]([C:17](=[O:19])[CH:18]=1)=[C:15]([OH:20])[CH:14]=[C:13]([OH:21])[C:12]=2[C@@H:22]1[CH2:26][CH2:25][N:24]([CH3:27])[C@H:23]1[CH2:28][OH:29]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 67409880HCID 67409880, compound

Product 1

HCID 67409879HCID 67409879, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The compound of example 61 (0.120 g, 0.227 mmol) was suspended in methanol (1 mL) and treated with ethereal HCl and the organic solvent was evaporated to afford the title compound, the hydrochloride salt.

Workup

  1. customthe organic solvent was evaporated

Sources & evidence

ORD record
ord-24f359f638594da79d09d826e8801799
Source dataset
uspto-grants-2014_12
Patent number
US08906953B2

Reaction notes

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