(Trifluoromethyl)benzene → trans-N-(4-hydroxymethyl-cyclohexylmethyl)-N-methyl-4-trifluoromethyl-benzenesulfonamide
Reaction equation
[CH3:1][NH:2][CH2:3][CH:4]1[CH2:5][CH2:6][CH:7]([CH2:10][OH:11])[CH2:8][CH2:9]1.[F:17][C:18]([c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1)([F:25])[F:26].[S:12](=[O:13])([Cl:14])([OH:15])=[O:16]>>[CH3:1][N:2]([CH2:3][CH:4]1[CH2:5][CH2:6][CH:7]([CH2:10][OH:11])[CH2:8][CH2:9]1)[S:12](=[O:13])(=[O:15])[c:22]1[cH:21][cH:20][c:19]([C:18]([F:17])([F:25])[F:26])[cH:24][cH:23]1Participants
4
Sources & evidence
- ORD record
- ord-4acf2e808e374194b66de491047d1c62
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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