HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 140154Generated: October 26, 2026
1,4-Dioxane → 4-Chloro-6-(3,3-difluoropyrrolidin-1-yl)pyrimidine
https://huagongshe.com/reaction/140154
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | 4,6-Dichloropyrimidine | HCID 70943 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 3,3-Difluoropyrrolidine | HCID 2782827 | — |
| Product | 4-Chloro-6-(3,3-difluoropyrrolidin-1-yl)pyrimidine | HCID 86617114 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
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| ORD ID | ord-48aaa8b636224dd98c6f2e663af5a57a |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
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