反应详情

25 g (143 mmol) of 1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone were dissolved in 750 ml of THF, 64.7 g (172 mmol) of phenyltrimethylammonium tribromide were added, and the mixture was stirred at room temperature for 15 h. The resultant precipitate was filtered, and the filtrate was evaporated to dryness. The residue was taken up in ethyl acetate, washed with 2× sat. sodium hydrogencarbonate solution and 1× sat. sodium chloride solution, the organic phase was dried over sodium sulfate and evaporated to dryness.

1. filtrationThe resultant precipitate was filtered
2. customthe filtrate was evaporated to dryness
3. washwashed with 2× sat. sodium hydrogencarbonate solution and 1× sat. sodium chloride solution
4. dry with materialthe organic phase was dried over sodium sulfate
5. customevaporated to dryness