HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminium lithium hydride → HCID 67323188, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | HCID 67323751 | HCID 67323751 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 67323188 | HCID 67323188 | — |
Reaction Steps
The preparation was carried out as already described using a 2N lithium aluminium hydride solution in THF starting from 30 mg (0.06 mmol) of ((2S,3S)-3-hydroxypyrrolidin-2-yl)-{4-[4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]piperidin-1-yl}methanone. The product was purified by means of preparative HPLC and is in the form of the hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08907098B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-3beb4fc1e3434a808a72517ef4ec76b1 |
| Source note | uspto-grants-2014_12 |