HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67323363, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Malonic acid, 3-chloropropyl-, diethyl ester | HCID 140413 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | HCID 53312286 | HCID 53312286 | — |
| Product | HCID 67323363 | HCID 67323363 | — |
Reaction Steps
The preparation was carried out analogously as described above starting from 200 mg (0.53 mmol) of 1-[4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]piperazine and 234 μl (0.1.06 mmol) of 2-(3-chloropropyl)malonic acid diethyl ester and subsequent reduction using lithium aluminium hydride prepared. The product is in the form of the hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08907098B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-15672ffc8e704750b03ca3868a781ab6 |
| Source note | uspto-grants-2014_12 |