HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 67325216, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 67322507 | HCID 67322507 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 67325216 | HCID 67325216 | — |
Reaction Steps
The protecting group was cleaved off as already described using TFA in DCM starting from 27 mg (0.06 mmol) of 4-[3-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)isoxazol-5-yl]piperazine-1-carboxylic acid tert-butyl ester from step d. The product is in the form of the TFA salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08907098B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-9d75e37e6abc46ffb0e36bbba6ea0ab1 |
| Source note | uspto-grants-2014_12 |