HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67324404, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 67324522 | HCID 67324522 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 67324404 | HCID 67324404 | — |
Reaction Steps
The protecting group was cleaved off as already described using HCl in dioxane starting from 120 mg (0.27 mmol) of 4-[4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,2,3-triazol-1-yl]piperidine-1-carboxylic acid tert-butyl ester from step a. The product was purified by means of preparative HPLC and is in the form of the hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08907098B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-1b6fe845b21c4dbfb0f4467a82243a7a |
| Source note | uspto-grants-2014_12 |