Formate → 2-{1-[4-(1,1,3,3-Tetramethylindan-5-yl)thiazol-2-yl]-piperidin-4-ylamino}ethanol

Participants

Role	Name	HCID	Charge
Reactant	Formate	HCID 283	—
Reactant	4,4,5,5-tetramethyl-2-(1,1,3,3-tetramethyl-2,3-dihydro-1H-inden-5-yl)-1,3,2-dioxaborolane	HCID 53250113	—
Reactant	2-(1-(4-Bromothiazol-2-yl)piperidin-4-ylamino)ethanol	HCID 67323340	—
Product	2-{1-[4-(1,1,3,3-Tetramethylindan-5-yl)thiazol-2-yl]-piperidin-4-ylamino}ethanol	HCID 67324463	—

Reaction Steps

The preparation is carried out as described above starting from 110 mg (0.29 mmol) of 2-[1-(4-bromothiazol-2-yl)piperidin-4-ylamino]ethanol and 98 mg (0.29 mmol) of 4,4,5,5-tetramethyl-2-(1,1,3,3-tetramethylindan-5-yl)-1,3,2-dioxaborolane. The product is in the form of the formate.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08907098B2
Source dataset	uspto-grants-2014_12
ORD ID	ord-057923e65b5148caa795dd9d19861c5e
Source note	uspto-grants-2014_12