Acetonitrile → 7'-Bromo-3'-(difluoromethoxy)spiro[2,6-dihydro-1,4-oxazine-5,5'-chromeno[2,3-c]pyridine]-3-amine
Reaction equation
[CH3:25][C:26]#[N:27].[CH3:42][CH2:43][O:44][C:45]([CH3:46])=[O:47].[Cs+:24].[F-:23].[F:28][C:29]([S:30]([F:31])(=[O:32])=[O:33])([C:34]([O:35][Si:36]([CH3:37])([CH3:38])[CH3:39])=[O:40])[F:41].[NH2:1][C:2]1=[N:3][C:4]2([c:5]3[cH:6][c:7]([Br:19])[cH:8][cH:9][c:10]3[O:11][c:12]3[cH:13][n:14][c:15]([OH:18])[cH:16][c:17]32)[CH2:20][O:21][CH2:22]1>>[NH2:1][C:2]1=[N:3][C:4]2([c:5]3[cH:6][c:7]([Br:19])[cH:8][cH:9][c:10]3[O:11][c:12]3[cH:13][n:14][c:15]([O:18][CH:29]([F:28])[F:41])[cH:16][c:17]32)[CH2:20][O:21][CH2:22]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-6ff3044ad31a4b4fb7020bff25b6da28
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…