HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2-((Dimethylamino)methyl)-1-(3-methoxyphenyl)cyclohexanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Propylene Glycol | HCID 1030 | — |
| Reactant | Cyclohexanol, 2-((dimethylamino)methyl)-1-(3-methoxyphenyl)-, hydrochloride (1:1) | HCID 9971980 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-((Dimethylamino)methyl)-1-(3-methoxyphenyl)cyclohexanol | HCID 5523 | — |
Reaction Steps
10 grams of the above formulation were prepared as follows: 0.5 g soy phospholipid was dissolved in 1.5 grams ethanol and 2 grams propylene glycol was added to this solution followed by addition of Vitamin E and mixing for 5 minutes. Then, 90 mg Tramadol HCl was added to this mixture. Water was added slowly with constant stirring by a Heidolph overhead stirrer. The composition is stirred for additional 10 minutes. The final composition contains 9 mg/g Tramadol HCl.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08911751B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-3958ead31632441c91e61d696c9d87c6 |
| Source note | uspto-grants-2014_12 |