Bromotrimethylsilane → HCID 67450329, compound

Participants

Reaction Steps

0.150 g (0.556 mmol) of ethyl (4-chlorophenyl)(1-cyanocyclopropyl)phosphinate was dissolved in 20 ml of chloroform, and 0.511 g (3.337 mmol) of bromotrimethylsilane was added. After stirring at room temperature for 18 hours, the solvent was removed, the residue was taken up in water and the solution was concentrated again by rotary evaporation. After column chromatography, 0.150 g (94.9% of theory) of (4-chlorophenyl)(1-cyanocyclopropyl)phosphinic acid was obtained.

Provenance & Evidence