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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1402750Generated: November 1, 2026

Lithium Hydroxide → HCID 66739710, compound

https://huagongshe.com/reaction/1402750

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantHCID 66739390HCID 66739390—
SolventTetrahydrofuranHCID 8028—
ProductHCID 66739710HCID 66739710100%

Reaction Steps

To a stirred solution of methyl 6-(1-hydroxy-1-methylethyl)pyridine-3-carboxylate (479 mg, 2.45 mmol) in THF, (10 mL) was added LiOH (2M aqueous solution, 1.35 mL, 2.70 mmol). After 4 hours the solvent was removed at reduced pressure to give the title compound (458 mg, 100%) that was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08912176B2
Source datasetuspto-grants-2014_12
ORD IDord-73eb9239b930413fa618af73ae1a45f1
Source noteuspto-grants-2014_12