Acetate → 5-(1-Methoxyimino-indan-5-yl)-4-pyridin-4-yl-furan-2-carbaldehyde

HRID 140276Notes

Reaction equation

HRID 140276 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH:19]=[O:20])[o:5][c:6]1-[c:7]1[cH:8][c:9]2[c:13]([cH:14][cH:15]1)[C:12](=[N:16][O:17][CH3:18])[CH2:11][CH2:10]2.[C:66]([O-:67])(=[O:68])[CH3:69].[C:71]([O-:72])(=[O:73])[CH3:74].[CH2:21]([Sn:22]([CH2:23][CH2:24][CH2:25][CH3:32])([c:26]1[cH:27][cH:28][n:29][cH:30][cH:31]1)[CH2:33][CH2:34][CH2:35][CH3:36])[CH2:37][CH2:38][CH3:39].[CH3:59][c:60]1[cH:61][cH:62][cH:63][cH:64][cH:65]1.[Pd+2:70].[c:40]1([P:41]([c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[cH:54][cH:55][cH:56][cH:57][cH:58]1>>[c:2]1(-[c:26]2[cH:27][cH:28][n:29][cH:30][cH:31]2)[cH:3][c:4]([CH:19]=[O:20])[o:5][c:6]1-[c:7]1[cH:8][c:9]2[c:13]([cH:14][cH:15]1)[C:12](=[N:16][O:17][CH3:18])[CH2:11][CH2:10]2

Participants

7

Reactant 6

HCID 175Acetate2×HCID 1140TolueneHCID 11776TriphenylphosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 27373184-(Tri-n-butylstannyl)pyridineHCID 867607594-Bromo-5-(1-methoxyimino-indan-5-yl)-furan-2-carbaldehyde

Product 1

HCID 867607605-(1-Methoxyimino-indan-5-yl)-4-pyridin-4-yl-furan-2-carbaldehyde

Sources & evidence

ORD record
ord-e24093bfe38c469baa1bc59ada1754b9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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