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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1402791Generated: October 31, 2026

4-(4-chlorophenyl)dihydro-2H-pyran-2,6(3H)-dione → HCID 45380988, compound

https://huagongshe.com/reaction/1402791

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-chlorophenyl)dihydro-2H-pyran-2,6(3H)-dioneHCID 104639—
Reactant4-Methoxy-o-phenylenediamineHCID 153404—
ProductHCID 45380988HCID 45380988—

Reaction Steps

By a procedure similar to that of example 1.4, starting from commercial 4-methoxy-1,2-phenylenediamine and 3-(4-chlorophenyl)glutaric anhydride, 3-(4-chlorophenyl)-4-(5-methoxy-2-benzimidazolyl)butanoic acid•HCl was obtained as light red solid, provided that cyclisation of the crude glutaramic acid was carried out with HCl in 1,4-dioxane at reflux for 1.5 h.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08912186B2
Source datasetuspto-grants-2014_12
ORD IDord-bb43f73478f245a980add1016b1d23c5
Source noteuspto-grants-2014_12