4-Chloro-1,2-diaminobenzene → HCID 45381204, compound

HRID 1402808Notes

Reaction equation

HRID 1402808 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH2:8])=[C:4]([NH2:9])[CH:3]=1.[Cl:10][C:11]1[CH:16]=[CH:15][C:14]([CH:17]2[CH2:23][C:22](=O)[O:21][C:19](=[O:20])[CH2:18]2)=[CH:13][C:12]=1[F:25]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]2[N:8]=[C:22]([CH2:23][CH:17]([C:14]3[CH:15]=[CH:16][C:11]([Cl:10])=[C:12]([F:25])[CH:13]=3)[CH2:18][C:19]([OH:21])=[O:20])[NH:9][C:4]=2[CH:3]=1.[ClH:1]

Participants

3

Reactant 2

HCID 72634-Chloro-1,2-diaminobenzeneHCID 54758301HCID 54758301, compound

Product 1

HCID 45381204HCID 45381204, compound

Procedure

By a procedure similar to that of example 1.4, starting from 4-chloro-1,2-phenylenediamine and 3-(4-chloro-3-fluorophenyl)glutaric anhydride, 4-(5-chloro-2-benzimidazolyl)-3-(4-chloro-3-fluorophenyl)butanoic acid•HCl was obtained as light red solid.

Sources & evidence

ORD record
ord-96f5482fc0b74f5e9e6d30512214682e
Source dataset
uspto-grants-2014_12
Patent number
US08912186B2

Reaction notes

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