4-Chloro-1,2-diaminobenzene → HCID 54758212, compound

HRID 1402809Notes

Reaction equation

HRID 1402809 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH2:8])=[C:4]([NH2:9])[CH:3]=1.[Cl:10][C:11]1[CH:16]=[CH:15][C:14]([CH:17]2[CH2:23][C:22](=O)[O:21][C:19](=[O:20])[CH2:18]2)=[CH:13][C:12]=1[C:25]([F:28])([F:27])[F:26]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]2[N:8]=[C:22]([CH2:23][CH:17]([C:14]3[CH:15]=[CH:16][C:11]([Cl:10])=[C:12]([C:25]([F:28])([F:26])[F:27])[CH:13]=3)[CH2:18][C:19]([OH:21])=[O:20])[NH:9][C:4]=2[CH:3]=1.[ClH:1]

Participants

3

Reactant 2

HCID 72634-Chloro-1,2-diaminobenzeneHCID 54758300HCID 54758300, compound

Product 1

HCID 54758212HCID 54758212, compound

Procedure

By a procedure similar to that of example 1.4, starting from 4-chloro-1,2-phenylenediamine and 3-(4-chloro-3-trifluoromethylphenyl)glutaric anhydride, 4-(5-chloro-2-benzimidazolyl)-3-(4-chloro-3-trifluoromethylphenyl)butanoic acid•HCl was obtained as light greyish solid.

Sources & evidence

ORD record
ord-e24cc919c6c14807ac5afa2f42f7ac59
Source dataset
uspto-grants-2014_12
Patent number
US08912186B2

Reaction notes

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