HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66759828, compound → HCID 12635770, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66759828 | HCID 66759828 | — |
| Solvent | Aceton-methanol | HCID 21894497 | — |
| Product | HCID 12635770 | HCID 12635770 | 72.5% |
Reaction Steps
Neat 2-[3-(4-chlorophenyl)-3-oxo-1-phenylpropyl]malonic acid (0.3 g) was heated to 160° C. with stirring for 1 h. After cooling to rt the crude was dissolved in acetone/methanol. Precipitation of product was effected by addition of dichloromethane. The precipitate was collected to afford 5-(4-chlorophenyl)-5-oxo-3-phenylpentanoic acid (0.19 g) as colourless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08912186B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-42511c1199214d8ca6c63a658bebdee6 |
| Source note | uspto-grants-2014_12 |