Diethyl Malonate → HCID 66759505, compound

HRID 1402861Notes

Reaction equation

[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[C:15](=[O:24])[CH:16]=[CH:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:25]([O:33][CH2:34][CH3:35])(=[O:32])[CH2:26][C:27]([O:29][CH2:30][CH3:31])=[O:28]>>[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[C:15](=[O:24])[CH2:16][CH:17]([CH:26]([C:27]([O:29][CH2:30][CH3:31])=[O:28])[C:25]([O:33][CH2:34][CH3:35])=[O:32])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 7761Diethyl Malonate

HCID 2780926HCID 2780926, compound

Product 1

HCID 66759505HCID 66759505, compound

Procedure

By a procedure similar to that of example 1.59.2, starting from 1-(2-benzyloxyphenyl)-3-phenylprop-2-en-1-one and diethyl malonate, diethyl 2-[3-(2-benzyloxyphenyl)-3-oxo-1-phenylpropyl]malonate was obtained as colourless solid.

Sources & evidence

ORD record: ord-1293107331fb445cbcdee8b92419fc39
Source dataset: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08912186B2

Reaction notes

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