Diethyl Malonate → HCID 66759437, compound

HRID 1402862Notes

Reaction equation

[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[C:15](=[O:25])[CH:16]=[CH:17][C:18]1[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][CH:19]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:26]([O:34][CH2:35][CH3:36])(=[O:33])[CH2:27][C:28]([O:30][CH2:31][CH3:32])=[O:29]>>[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[C:15](=[O:25])[CH2:16][CH:17]([CH:27]([C:28]([O:30][CH2:31][CH3:32])=[O:29])[C:26]([O:34][CH2:35][CH3:36])=[O:33])[C:18]1[CH:19]=[CH:20][C:21]([Cl:24])=[CH:22][CH:23]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 7761Diethyl Malonate

HCID 2780939HCID 2780939, compound

Product 1

HCID 66759437HCID 66759437, compound

Procedure

By a procedure similar to that of example 1.59.2, starting from 1-(2-benzyloxyphenyl)-3-(4-chlorophenyl)prop-2-en-1-one and diethyl malonate, diethyl 2-[3-(2-benzyloxyphenyl)-1-(4-chlorophenyl)-3-oxopropyl]malonate was obtained as colourless solid.

Sources & evidence

ORD record: ord-007c7b9a91a6429ab84a97bc2283a6f9
Source dataset: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08912186B2

Reaction notes

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