Diethyl Malonate → HCID 66759202, compound

HRID 1402864Notes

Reaction equation

[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:11](=[O:20])[CH:12]=[CH:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.[C:21]([O:29][CH2:30][CH3:31])(=[O:28])[CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24]>>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:11](=[O:20])[CH2:12][CH:13]([CH:22]([C:23]([O:25][CH2:26][CH3:27])=[O:24])[C:21]([O:29][CH2:30][CH3:31])=[O:28])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

Reactant 2

HCID 7761Diethyl Malonate

HCID 236814HCID 236814, compound

Product 1

HCID 66759202HCID 66759202, compound

Procedure

By a procedure similar to that of example 1.59.2, starting from 1-(2-naphthalenyl)-3-phenylprop-2-en-1-one and diethyl malonate, diethyl 2-[3-(2-naphthalenyl)-3-oxo-1-phenylpropyl]malonate was obtained as colourless solid.

Sources & evidence

ORD record: ord-1c1633a3909841dfb505b09b3cde4386
Source dataset: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08912186B2

Reaction notes

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