4-Chlorobenzaldehyde → HCID 621357, compound

HRID 1402876Notes

Reaction equation

[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=O)=[CH:4][CH:3]=1.[CH3:10][C:11]([C:13]1[CH:18]=[CH:17][C:16]([F:19])=[CH:15][CH:14]=1)=[O:12]>>[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[CH:10][C:11]([C:13]2[CH:18]=[CH:17][C:16]([F:19])=[CH:15][CH:14]=2)=[O:12])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 77264-Chlorobenzaldehyde

HCID 98284'-Fluoroacetophenone

Product 1

HCID 621357HCID 621357, compound

Procedure

By a procedure similar to that of example 1.59.1, starting from 4-chlorobenzaldehyde and commercial 4-fluoroacetophenone, 3-(4-chlorophenyl)-1-(4-fluorophenyl)prop-2-en-1-one was obtained as yellowish solid.

Sources & evidence

ORD record: ord-29c7f3a860634dba9657f62e91ead9be
Source dataset: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08912186B2

Reaction notes

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