3-[4-(Methylsulfanyl)phenyl]-1-phenylpropan-1-one → HCID 131732161, compound

HRID 1402895Notes

Reaction equation

HRID 1402895 reaction equation
CSC1C=CC(CCC(C2C=CC=CC=2)=O)=CC=1.[CH3:19][S:20][C:21]1[CH:26]=[CH:25][C:24]([CH2:27][CH2:28]/[C:29](/[C:36]2[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=2)=[CH:30]/[C:31]([O:33][CH2:34][CH3:35])=[O:32])=[CH:23][CH:22]=1>>[CH3:19][S:20][C:21]1[CH:22]=[CH:23][C:24]([CH2:27][CH2:28]/[C:29](/[C:36]2[CH:37]=[CH:38][CH:39]=[CH:40][CH:41]=2)=[CH:30]\[C:31]([O:33][CH2:34][CH3:35])=[O:32])=[CH:25][CH:26]=1

Participants

3

Reactant 2

HCID 247259643-[4-(Methylsulfanyl)phenyl]-1-phenylpropan-1-oneHCID 131732162HCID 131732162, compound

Product 1

HCID 131732161HCID 131732161, compound

Procedure

By a procedure similar to that of example 1.85.3, starting from 3-[4-(methylthio)phenyl]-1-phenylpropan-1-one, (Z)-ethyl 5-[4-(methylthio)phenyl]-3-phenylpent-2-enoate and (E)-ethyl 5-[4-(methylthio)phenyl]-3-phenylpent-2-enoate were obtained as colourless oils.

Sources & evidence

ORD record
ord-3dade121cc4b4b9fa4efddf43ee2356a
Source dataset
uspto-grants-2014_12
Patent number
US08912186B2

Reaction notes

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