4-Chloroaniline → HCID 12646051, compound
Reaction equation
[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1.[C:9]([O:13][CH2:14][CH3:15])(=[O:12])[CH:10]=[CH2:11]>>[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH:6][CH2:11][CH2:10][C:9]([O:13][CH2:14][CH3:15])=[O:12])=[CH:4][CH:3]=1Participants
3
Procedure
By a procedure similar to that of example 1.116.1, starting from 4-chloroaniline and ethyl acrylate, ethyl N-(4-chlorophenyl)-3-aminopropionate was obtained as light tan oil.
Sources & evidence
- ORD record
- ord-33f236f98183466e800c3d1359598f15
- Source dataset
- uspto-grants-2014_12
- Patent number
- US08912186B2
Reaction notes
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