4-Chlorobenzaldehyde → HCID 54366908, compound
Reaction equation
[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=O)=[CH:4][CH:3]=1.[F:10][C:11]([F:22])([F:21])[C:12]1[CH:17]=[CH:16][C:15]([C:18](=[O:20])[CH3:19])=[CH:14][CH:13]=1>>[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[CH:19][C:18]([C:15]2[CH:14]=[CH:13][C:12]([C:11]([F:21])([F:22])[F:10])=[CH:17][CH:16]=2)=[O:20])=[CH:4][CH:3]=1Participants
3
Procedure
By a procedure similar to that of example 1.59.1, starting from 4-chlorobenzaldehyde and p-(trifluoromethyl)acetophenone, 3-(4-chlorophenyl)-1-(4-(trifluoromethyl)-phenyl)prop-2-en-1-one was obtained as beige coloured solid.
Sources & evidence
- ORD record
- ord-0c8b969c879f4a8ba0ba895e4fbb4d8e
- Source dataset
- uspto-grants-2014_12
- Patent number
- US08912186B2
Reaction notes
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