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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1402951Generated: November 2, 2026

1-(4-(Trifluoromethyl)phenyl)ethan-1-one → 3-(4-Phenylthiophen-2-yl)-1-(4-(trifluoromethyl)phenyl)prop-2-en-1-one

https://huagongshe.com/reaction/1402951

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-(Trifluoromethyl)phenyl)ethan-1-oneHCID 69731—
Reactant4-Phenylthiophene-2-carbaldehydeHCID 5009467—
Product3-(4-Phenylthiophen-2-yl)-1-(4-(trifluoromethyl)phenyl)prop-2-en-1-oneHCID 66759394—

Reaction Steps

By a procedure similar to that of example 1.59.1, starting from 4-phenylthiophene-2-carbaldehyde and p-(trifluoromethyl)acetophenone, 3-(4-phenylthiophen-2-yl)-1-(4-(trifluoromethyl)phenyl)prop-2-en-1-one was obtained as yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08912186B2
Source datasetuspto-grants-2014_12
ORD IDord-a9d0e634f97b424d9a84369c56a7651f
Source noteuspto-grants-2014_12