Hydrochloric Acid → HCID 66760919, compound

Participants

Reaction Steps

A solution of dimethyl 2-(1-(4-chlorophenyl)-3-(4-(methoxymethoxy)phenyl)-3-oxopropyl)malonate (0.3 g) in methanol (10 ml) was treated with 10% HCl (2 ml) and the resulting mixture was refluxed for 2 h. After cooling to room temperature the solvent was removed, the residue was extracted with ethyl acetate, and dried (magnesium sulphate). After concentration the crude (0.3 g yellow oil) was used for the next step without further purification.

Provenance & Evidence