HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Phenylmethyl)-1H-indazol-5-amine → 1-benzyl-1H-indazol-5-yl(7-iodoquinazolin-4-yl)-amine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Phenylmethyl)-1H-indazol-5-amine | HCID 212069 | — |
| Reactant | 4-Chloro-7-iodoquinazoline | HCID 21874802 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1-benzyl-1H-indazol-5-yl(7-iodoquinazolin-4-yl)-amine hydrochloride | HCID 21952170 | 76.7% |
Reaction Steps
Prepared according to Procedure A from 4-Chloro-7-iodoquinazoline (0.42 g) and 1-benzyl-1H-indazol-5-ylamine (0.323 g) in acetonitrile (20 ml) at reflux under nitrogen for 18 hours. The mixture was cooled and filtered to give the title compound (0.57 g); m/z (M+1+) 478.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08912205B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-8d44c46262934439807c55b0db07443e |
| Source note | uspto-grants-2014_12 |