Hydrochloric Acid → HCID 58303983, compound

HRID 1404095Notes

Reaction equation

HRID 1404095 reaction equation
[Br:1][C:2]1[C:3]([O:19][CH3:20])=[C:4]2[C:8](=[C:9]([F:11])[CH:10]=1)[N:7]([CH3:12])[CH:6]=[C:5]2[CH:13]([CH3:18])[C:14]([O:16]C)=[O:15].[OH-].[K+].Cl>O>[Br:1][C:2]1[C:3]([O:19][CH3:20])=[C:4]2[C:8](=[C:9]([F:11])[CH:10]=1)[N:7]([CH3:12])[CH:6]=[C:5]2[CH:13]([CH3:18])[C:14]([OH:16])=[O:15]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14797Potassium HydroxideHCID 58303957HCID 58303957, compound

Product 1

HCID 58303983HCID 58303983, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To the solution of 9-2 (0.5 g, 1.5 mmol) in water (10 mL) was added 2N KOH (10 mL). The mixture was stirred at room temperature for 1 h. The mixture was neutralized with HCl to pH:5. The precipitate was filtered and dried. 9-3 (210 mg, crude) was obtained as a yellow solid.

Workup

  1. filtrationThe precipitate was filtered
  2. customdried
  3. custom9-3 (210 mg, crude) was obtained as a yellow solid

Sources & evidence

ORD record
ord-7df788adfdf64768a9b6a6ba61b92d4d
Source dataset
uspto-grants-2014_12
Patent number
US08912220B2

Reaction notes

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