HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(1-ethyl-6-fluoro-4-hydroxy-1H-indol-3-yl)-1-morpholinoethanone → 1-ethyl-6-fluoro-3-(2-morpholinoethyl)-1H-indol-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(1-ethyl-6-fluoro-4-hydroxy-1H-indol-3-yl)-1-morpholinoethanone | HCID 58304026 | — |
| Reactant | 2-(4-Benzyloxy-5-fluoro-1H-indol-3-yl)-N,N-dimethylethanamine | HCID 66927088 | — |
| Product | 1-ethyl-6-fluoro-3-(2-morpholinoethyl)-1H-indol-4-ol | HCID 50996167 | 27% |
Reaction Steps
Following the procedure used to prepare compound 1-7a (step 6 scheme 1), compound 11-4 gave compound 11-5 (41 mg, 27%) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08912220B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-8fa8d67763204b3689ff946172cf665c |
| Source note | uspto-grants-2014_12 |