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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1404100Generated: November 3, 2026

2-(1-ethyl-6-fluoro-4-hydroxy-1H-indol-3-yl)-1-morpholinoethanone → 1-ethyl-6-fluoro-3-(2-morpholinoethyl)-1H-indol-4-ol

https://huagongshe.com/reaction/1404100

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(1-ethyl-6-fluoro-4-hydroxy-1H-indol-3-yl)-1-morpholinoethanoneHCID 58304026—
Reactant2-(4-Benzyloxy-5-fluoro-1H-indol-3-yl)-N,N-dimethylethanamineHCID 66927088—
Product1-ethyl-6-fluoro-3-(2-morpholinoethyl)-1H-indol-4-olHCID 5099616727%

Reaction Steps

Following the procedure used to prepare compound 1-7a (step 6 scheme 1), compound 11-4 gave compound 11-5 (41 mg, 27%) as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08912220B2
Source datasetuspto-grants-2014_12
ORD IDord-8fa8d67763204b3689ff946172cf665c
Source noteuspto-grants-2014_12