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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1404151Generated: October 30, 2026

1-ethyl-6-fluoro-3-(2-(isoindolin-2-yl)ethyl)-1H-indol-4-ol → 1-ethyl-6-fluoro-3-(2-hydroxyethyl)-1H-indol-4-ol

https://huagongshe.com/reaction/1404151

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-ethyl-6-fluoro-3-(2-(isoindolin-2-yl)ethyl)-1H-indol-4-olHCID 50996350—
Reactant2-(4-(Benzyloxy)-1-ethyl-6-fluoro-1H-indol-3-yl)ethanolHCID 58303962—
Product1-ethyl-6-fluoro-3-(2-hydroxyethyl)-1H-indol-4-olHCID 6692720199%

Reaction Steps

Following the procedure (step 3 scheme 31 used to prepare compound 31-4 compound 26-5 gave compound 39-2 (318 mg, 99%) as a light purple solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08912220B2
Source datasetuspto-grants-2014_12
ORD IDord-0b72e20f982847deb0a90c5536168a01
Source noteuspto-grants-2014_12