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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1404156Generated: November 3, 2026

2-(7-propyl-3,7-dihydro-2H-[1,4]dioxino[2,3-e]indol-9-yl)acetic acid → 2-(7-propyl-3,7-dihydro-2H-[1,4]dioxino[2,3-e]indol-9-yl)acetamide

https://huagongshe.com/reaction/1404156

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(7-propyl-3,7-dihydro-2H-[1,4]dioxino[2,3-e]indol-9-yl)acetic acidHCID 66927190—
Reactant2-(4-(benzyloxy)-1-ethyl-6-fluoro-1H-indol-3-yl)-1-(isoindolin-2-yl)ethanoneHCID 67235028—
Product2-(7-propyl-3,7-dihydro-2H-[1,4]dioxino[2,3-e]indol-9-yl)acetamideHCID 66927226100%

Reaction Steps

Following the procedure (step 1, scheme 31) used to prepare compound 31-2, compound 40-5 gave compound 40-6 in 100% yield as yellow oil. LCMS: calc 274.1 found 275.0 [MH]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08912220B2
Source datasetuspto-grants-2014_12
ORD IDord-bfd21bb846554d219a96d17ea1613b8b
Source noteuspto-grants-2014_12