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HRID1404340

反应详情

EQUATION

反应方程式

HRID 1404340 的结构方程式

REACTANTS

反应物

2
反应SMILES：Cl
HCID313

Hydrochloric Acid

ClH

反应SMILES：CC(C)(C)OC(=O)NCCN[C@H]1CC[C@H](CC(=O)N[C@H]2Cc3cccc(C(=O)O)c3OB2O)CC1
HCID178453691

未命名化合物

PRODUCTS

产物

1
反应SMILES：NCCN[C@H]1CC[C@H](CC(=O)N[C@H]2Cc3cccc(C(=O)O)c3OB2O)CC1
HCID178511351

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
反应SMILES：C1COCCO1
溶剂HCID31275

1,4-Dioxane

C4H8O2

PROCEDURE

实验过程

To (R)-3-(2-(trans-4-(2-(tert-butoxycarbonylamino)ethylamino)cyclohexyl)acetamido)-2-hydroxy-3,4-dihydro-2H-benzo[e][1,2]oxaborinine-8-carboxylic acid (20 mg) in a flask was added 1 mL 4N HCl in dioxane. The resulting reaction mixture was stirred at RT for 2 hr. The solvent was removed in vacuo and the residue was purified by reverse phase preparative HPLC and dried using lyophilization. ESI-MS m/z 390 (MH)+.

WORKUP

后处理

  1. customThe resulting reaction mixture
  2. customThe solvent was removed in vacuo
  3. customthe residue was purified by reverse phase preparative HPLC
  4. customdried