HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 4-formylpiperidine-1-carboxylate → HCID 178520740, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 4-formylpiperidine-1-carboxylate | HCID 1514430 | — |
| Reactant | HCID 178511528 | HCID 178511528 | — |
| Product | HCID 178520740 | HCID 178520740 | — |
Reaction Steps
Prepared from (R)-3-(2-(trans-4-aminocyclohexyl)acetamido)-2-hydroxy-3,4-dihydro-2H-benzo[e][1,2]oxaborinine-8-carboxylic acid (Example 6) and tert-butyl 4-formylpiperidine-1-carboxylate following the procedure in Example 27. Boc group was removed by treatment with 4N HCl in dioxane. The product was purified using reverse phase HPLC to afford the titled compound. ESI-MS m/z 444 (MH)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08912169B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-41e7a9e0d1f14bf0a1044c608950db75 |
| Source note | uspto-grants-2014_12 |