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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1404430Generated: October 31, 2026

Sulfuric Acid → 2-(Pyridin-4-yl)morpholine

https://huagongshe.com/reaction/1404430

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSulfuric AcidHCID 1118—
ReactantHCID 67289794HCID 67289794—
Product2-(Pyridin-4-yl)morpholineHCID 21750497—

Reaction Steps

2-(Pyridin-4-yl)morpholine is prepared by treating 2-(2-hydroxyethylamino)-1-(pyridin-4-yl)ethanol with fuming sulfuric acid at 170° C. according to F. Zymalkowski and F. Koppe (Arch. Pharmaz. 1961, 294, 453-468).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08912329B2
Source datasetuspto-grants-2014_12
ORD IDord-794e170b452e443eb779609893f1ab9e
Source noteuspto-grants-2014_12