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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1404434Generated: November 1, 2026

Dimethylformamide → HCID 1266787, compound

https://huagongshe.com/reaction/1404434

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantPhenethyl bromideHCID 7666—
Reactant2-PyrrolidoneHCID 12025—
ReactantSodium hydrideHCID 24758—
ProductHCID 1266787HCID 1266787—

Reaction Steps

1-(2-(Pyridin-2-yl)ethyl)pyrrolidin-2-one is prepared from 2-pyrrolidone and 2-bromo-ethylbenzene in N,N-dimethylformamide in the presence of sodium hydride (according to M. Matsukawa et al., NeuroToxicology 2004, 25, 293-302).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08912329B2
Source datasetuspto-grants-2014_12
ORD IDord-86a955769c3341a29d37ace735ba5b8a
Source noteuspto-grants-2014_12