Phenethylamine → HCID 49849019, compound

HRID 1404440Notes

Reaction equation

HRID 1404440 reaction equation
[CH:1]([CH:3]([CH2:9][CH3:10])[CH2:4][C:5]([O:7]C)=O)=O.[C:11]1([CH2:17][CH2:18][NH2:19])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>C(O)(=O)C>[CH2:9]([C:3]1[CH2:1][N:19]([CH2:18][CH2:17][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:5](=[O:7])[CH:4]=1)[CH3:10]

Participants

4

Reactant 2

HCID 1001PhenethylamineHCID 11084006Methyl 3-formylpentanoate

Product 1

HCID 49849019HCID 49849019, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

4-Ethyl-1-phenethyl-1H-pyrrol-2(5H)-one is synthesized by a cyclocondensation between methyl 3-formylpentanoate and 2-phenylethylamine in glacial acetic acid at 70° C. according to a procedure of R. Fisher (DE 4127111, 1992)

Sources & evidence

ORD record
ord-5fe3b947b996482ca93872696e994044
Source dataset
uspto-grants-2014_12
Patent number
US08912329B2

Reaction notes

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