2-(2-Benzothiazolylthio)acetic acid → 2-(Benzothiazol-2-ylsulfanyl)-1-(2-methyl-3,4-dihydro-2H-quinolin-1-yl)-ethanone

HRID 1404928Notes

Reaction equation

HRID 1404928 reaction equation
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][CH2:11][C:12]([OH:14])=O.[CH3:15][CH:16]1[CH2:25][CH2:24][C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[NH:17]1>>[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][CH2:11][C:12]([N:17]1[C:18]2[C:23](=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH2:24][CH2:25][CH:16]1[CH3:15])=[O:14]

Participants

3

Reactant 2

HCID 805252-(2-Benzothiazolylthio)acetic acidHCID 962892-Methyl-1,2,3,4-tetrahydroquinoline

Product 1

HCID 594678952-(Benzothiazol-2-ylsulfanyl)-1-(2-methyl-3,4-dihydro-2H-quinolin-1-yl)-ethanoneYield 40%

Procedure

The title compound was synthesized according to General Procedure B using 2-(benzo[d]thiazol-2-ylthio)acetic acid and 2-methyl-1,2,3,4-tetrahydroquinoline to yield 40 as a pale yellow solid (0.32 g, 40%); MS m/z: 355 (M+H)+. Anal. Calcd. For, C19H18N2OS2: C, 64.38; H, 5.12; N, 7.90; S, 18.09. Found: C, 64.38; H, 5.22; N, 7.85; S, 17.93.

Workup

  1. customThe title compound was synthesized

Sources & evidence

ORD record
ord-f2a59f40cb4b43358b29769dfd97ec07
Source dataset
uspto-grants-2014_12
Patent number
US08916550B2

Reaction notes

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