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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1405010Generated: October 31, 2026

2-Amino-4-chloro-6-methylpyrimidine → HCID 21846321, compound

https://huagongshe.com/reaction/1405010

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-4-chloro-6-methylpyrimidineHCID 21810—
Reactant3-(Trifluoromethyl)phenylboronic acidHCID 2734388—
ProductHCID 21846321HCID 21846321—

Reaction Steps

The title compound is synthesized according to general procedure GP4 starting from 2.0 g (14 mmol) 2-amino-4-chloro-6-methylpyrimidine and 3.4 g (18 mmol) 3-trifluoromethyl-phenyl boronic acid. Yield after extraction: 5.0 g (99%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08916548B2
Source datasetuspto-grants-2014_12
ORD IDord-542f247e211f4c43b68f887a50e87e3b
Source noteuspto-grants-2014_12