HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Iodosuccinimide → HCID 58513548, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Iodosuccinimide | HCID 120273 | — |
| Reactant | 3-(2-Amino-6-methylpyrimidin-4-yl)benzonitrile | HCID 53425031 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 58513548 | HCID 58513548 | — |
Reaction Steps
The title compound is synthesized according to general procedure GP1 starting from 3.2 g (12 mmol) 4-methyl-6-(3-cyano-phenyl)-pyrimidin-2-ylamine and 2.8 g (13 mmol) NIS. Yield after chromatography on silica gel with DCM/MeOH: 3.5 g (78%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08916548B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-cd5a1ee86ab1452d85e3b5de959ef50c |
| Source note | uspto-grants-2014_12 |