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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1405017Generated: October 31, 2026

N-Iodosuccinimide → HCID 58513139, compound

https://huagongshe.com/reaction/1405017

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-IodosuccinimideHCID 120273—
ReactantHCID 58513173HCID 58513173—
SolventDichloromethane methanolHCID 21226129—
ProductHCID 58513139HCID 58513139—

Reaction Steps

The title compound is synthesized according to general procedure GP1 starting from 3.2 g (11 mmol) 4-methyl-6-(3,5-dimethyl-phenyl)-pyrimidin-2-ylamine and 2.5 g (11 mmol) NIS. Yield after chromatography on silica gel with DCM/MeOH: 1.1 g (31%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08916548B2
Source datasetuspto-grants-2014_12
ORD IDord-2eb95cfa888e4076b96917b5a3c5c698
Source noteuspto-grants-2014_12