HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58513342, compound → HCID 58513336, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58513342 | HCID 58513342 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 58513336 | HCID 58513336 | — |
Reaction Steps
The title compound is synthesized according to general procedure GP8 starting from 130 mg (0.47 mmol) 4-[2-amino-6-ethyl-5-(6-methyl-pyridin-3-ylethynyl)-pyrimidin-4-yl]-2-fluoro-benzoic acid methyl ester using 470 μL (0.47 mmol) 1 N NaOH in 3 mL THF. The product precipitates from the reaction mixture and is isolated by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08916548B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-9b62e3e259204349b010dad5ac04e1f8 |
| Source note | uspto-grants-2014_12 |