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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1405045Generated: November 1, 2026

HCID 67004025, compound → HCID 67004490, compound

https://huagongshe.com/reaction/1405045

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67004025HCID 67004025—
SolventTetrahydrofuranHCID 8028—
ProductHCID 67004490HCID 67004490—

Reaction Steps

The title compound is synthesized according to general procedure GP8 starting from 238 mg (0.59 mmol) 4-[2-amino-6-ethyl-5-(6-methylamino-pyridin-3-ylethynyl)-pyrimidin-4-yl]-2-fluoro-benzoic acid methyl ester using 0.88 mL (0.88 mmol) 1 N NaOH in 3 mL THF.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08916548B2
Source datasetuspto-grants-2014_12
ORD IDord-fa602962baf845868bde487f8b6cebc2
Source noteuspto-grants-2014_12