HCID 70976411, compound → HCID 89155153, compound

HRID 1405211Notes

Reaction equation

HRID 1405211 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([N+:8]([O-])=O)[CH:5]=[C:4]([CH2:11][S:12]([CH3:15])(=[O:14])=[O:13])[CH:3]=1>CO>[Cl:1][C:2]1[CH:7]=[C:6]([CH:5]=[C:4]([CH2:11][S:12]([CH3:15])(=[O:14])=[O:13])[CH:3]=1)[NH2:8]

Participants

3

Reactant 1

HCID 70976411HCID 70976411, compound

Product 1

HCID 89155153HCID 89155153, compoundYield 93.9%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of 1-chloro-3-[(methylsulfonyl)methyl]-5-nitrobenzene (4.6 g) in methanol (40 mL) was treated similarly as described in example 35.3. Crystallization of the crude product (4.6 g) from diethyl ether furnished the pure title compound (3.8 g)

Workup

  1. customCrystallization of the crude product (4.6 g) from diethyl ether

Sources & evidence

ORD record
ord-1337164f9662418ca29df3494d35fa22
Source dataset
uspto-grants-2014_12
Patent number
US08916557B2

Reaction notes

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