HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Butanol → 4-(2-Butoxy-4-fluorophenyl)-N-{3-[(methylsulfonyl)-methyl]phenyl}-1,3,5-triazin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Butanol | HCID 263 | — |
| Reactant | 4-(2,4-difluorophenyl)-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amine | HCID 70976524 | — |
| Product | 4-(2-Butoxy-4-fluorophenyl)-N-{3-[(methylsulfonyl)-methyl]phenyl}-1,3,5-triazin-2-amine | HCID 66576758 | — |
Reaction Steps
Starting with 4-(2,4-difluorophenyl)-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amine (75 mg; 0.19 mmol), intermediate 42.1, and butan-1-ol (74 μl; 0.773 mmol), example 44 was prepared analogously to the procedure for the preparation of example 42.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08916557B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-16cd2bbdfc6242c4a7b5f9f51f5a80cd |
| Source note | uspto-grants-2014_12 |