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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1405247Generated: November 1, 2026

3-Fluoro-5-(trifluoromethyl)benzyl alcohol → HCID 66575976, compound

https://huagongshe.com/reaction/1405247

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-5-(trifluoromethyl)benzyl alcoholHCID 589176—
Reactant4-(2,4-difluorophenyl)-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amineHCID 70976524—
ProductHCID 66575976HCID 66575976—

Reaction Steps

Starting with 4-(2,4-difluorophenyl)-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amine (75 mg; 0.197 mmol), intermediate 42.1, and 3-fluoro-5-(trifluoromethyl)benzyl alcohol (158 mg; 0.789 mmol), example 78 was prepared analogously to the procedure for the preparation of example 42.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08916557B2
Source datasetuspto-grants-2014_12
ORD IDord-4a2d35b18ece418aaa75c913e6d624e2
Source noteuspto-grants-2014_12