Methanol → 1-(4-Amino-2-chlorophenyl)-3-bromopyridin-2-one

HRID 140540Notes

Reaction equation

[Br:1][c:2]1[c:3](=[O:18])[n:4](-[c:8]2[c:9]([Cl:17])[cH:10][c:11]([N+:14]([O-:15])=[O:16])[cH:12][cH:13]2)[cH:5][cH:6][cH:7]1.[CH3:26][OH:27].[OH2:19].[OH2:20].[Sn:21]([Cl:22])([Cl:23])([Cl:24])[Cl:25]>>[Br:1][c:2]1[c:3](=[O:18])[n:4](-[c:8]2[c:9]([Cl:17])[cH:10][c:11]([NH2:14])[cH:12][cH:13]2)[cH:5][cH:6][cH:7]1

Participants

Reactant 4

HCID 887Methanol

HCID 962Water2×

HCID 24287Tin tetrachloride

HCID 595365983-Bromo-1-(2-chloro-4-nitrophenyl)pyridin-2(1H)-one

Product 1

HCID 595366091-(4-Amino-2-chlorophenyl)-3-bromopyridin-2-one

Sources & evidence

ORD record: ord-12e15be44a7d4efe97a4bc7747501592
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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