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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1405633Generated: November 2, 2026

1,2,3,4-Tetrahydroquinoline-8-carboxylic acid → HCID 86723071, compound

https://huagongshe.com/reaction/1405633

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2,3,4-Tetrahydroquinoline-8-carboxylic acidHCID 2785589—
Reactant6-[(R)-5-(3-amino-propyl)-2-oxo-oxazolidin-3-yl]-4H-benzo[1,4]thiazin-3-oneHCID 67303587—
ProductHCID 86723071HCID 8672307185%

Reaction Steps

Starting from 1,2,3,4-tetrahydroquinoline-8-carboxylic acid and 6-[(R)-5-(3-amino-propyl)-2-oxo-oxazolidin-3-yl]-4H-benzo[1,4]thiazin-3-one (described in WO 2010/041219) and using Procedure D, the title compound was obtained as a beige solid (114 mg; 85% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08916573B2
Source datasetuspto-grants-2014_12
ORD IDord-cda52ab3017341739cf173fc4131c82c
Source noteuspto-grants-2014_12