1,1-bis(1,1-dimethylethoxy)-N,N,N-trimethylamine → HCID 68358107, compound

HRID 1406009Notes

Reaction equation

[CH3:1][N:2]1[C:6]2[C:7](=[O:12])[CH2:8][CH2:9][CH2:10][CH2:11][C:5]=2[C:4]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[N:3]1.C(O[CH:23](OC(C)(C)C)[N:24]([CH3:26])[CH3:25])(C)(C)C>CN(C=O)C>[CH3:23][N:24](/[CH:26]=[C:8]1\[CH2:9][CH2:10][CH2:11][C:5]2[C:4]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[N:3][N:2]([CH3:1])[C:6]=2[C:7]\1=[O:12])[CH3:25]

Participants

Conditions

Temperature: 80 °C

Procedure

To a solution of ethyl 1-methyl-8-oxo-1,4,5,6,7,8-hexahydrocyclohepta[c]pyrazole-3-carboxylate (210 mg, 0.94 mmol) in DMF (2 mL), N,N-dimethylformamide di-tertbutyl acetal (0.68 mL, 2.82 mmol) was added. The mixture was stirred at 80° C. for 3 h. Solvent was removed under reduced pressure and the residue used without further purification.

Workup

customSolvent was removed under reduced pressure
customthe residue used without further purification

Sources & evidence

ORD record: ord-e4be69b2b02c49c69fa74c1292ea0c27
Source dataset: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08916577B2

Reaction notes

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