Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1406023Generated: November 1, 2026

Hydrochloric Acid → HCID 86701838, compound

https://huagongshe.com/reaction/1406023

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 68358225HCID 68358225—
SolventMethanolHCID 887—
SolventTetrahydrofuranHCID 8028—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 86701838HCID 86701838—

Reaction Steps

To a solution of tert-butyl[(2S)-2-({[9-({2-methoxy-4-[(1-methylpiperidin-4-yl)carbamoyl]phenyl}amino)-1-methyl-1,4,5,6-tetrahydropyrazolo[4′,3′:6,7]cyclohepta[1,2-d]pyrimidin-3-yl]carbonyl}amino)-2-phenylethyl]carbamate (0.010 g, 0.014 mmol) in MeOH (0.2 mL) and THF (0.5 mL), 4M HCl in dioxane (0.2 mL) was added. The mixture was stirred at room temperature for 4 h. The organic solvent was evaporated to dryness to give the title compound in quantitative yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08916577B2
Source datasetuspto-grants-2014_12
ORD IDord-f4b93adecfc84bb5a27320f3d308d5a1
Source noteuspto-grants-2014_12